Boehringer Ingelheim
Manager - CMC Competitive Intelligence (m/w/x)
Teilzeitnur vor OrtSenior
Biberach
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Dein persönlicher KI-Karriere-Agent
BOBoehringer Ingelheim
Postdoc Mass Spectrometry and Characterisation (m/w/x)
TeilzeitBefristeter VertragVor OrtBerufserfahren
Nejo KI-Zusammenfassung
Mass spectrometry and protein characterization for next-gen biotherapeutics. PhD in related science with hands-on mass spec and chromatography expertise required. Focus on structure-function relationships, advanced analytical technologies, and data evaluation software.
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Anforderungen
- University degree in biochemistry, protein chemistry, analytical chemistry, bioinformatics, structural biology, pharmaceutical sciences, or related scientific discipline with PhD
- Strong scientific background in therapeutic protein or biologics characterization, ideally including monoclonal antibodies, antibody-derived formats, recombinant proteins, or other complex biologic modalities
- Hands-on expertise with advanced analytical technologies including mass spectrometry-based protein analytics (peptide mapping, intact and subunit level), chromatography (SEC, IEX, RP, HIC), and related advanced analytical technologies, including corresponding relevant data evaluation software packages such as Chromeleon, Empower, and UniFi. Practical experience with the GeneData Biologics Suite (such as Expressionist, Screener, Chromatics) would be an advantage.
- Comprehensive understanding of structure-function relationships of biotherapeutics, higher-order structure, protein stability, degradation pathways, molecular liabilities, critical quality attributes, and functional characterization of biologics
- Natural curiosity for scientific exploration, conceptual thinking, scientific rigor, and enthusiasm for building new approaches that connect experimental protein analytics with digital and predictive technologies
- Fluency in both German and English, written and spoken
Aufgaben
- Contribute to advanced characterization of next-generation biotherapeutics
- Deepen understanding of structure-function relationships
- Drive mass spectrometry and protein physicochemical characterization
- Drive chromatographical and electrophoretic characterization
- Lead and drive innovative scientific projects
- Focus on structure-function relationships and predictive assessment
- Ensure effective implementation within an interdisciplinary team
- Approach scientific questions with curiosity and an open mind
- Thoroughly investigate underlying causalities
- Identify actionable insights
- Translate insights into impactful contributions
- Collaborate with internal and external stakeholders
- Explore application solutions with data scientists and digital experts
- Explore AI-enabled interpretation approaches
- Explore similarity profiling
- Explore in silico prediction concepts
- Drive project planning
- Drive milestone tracking
- Drive stakeholder communication
- Drive scientific decision-making
- Prepare high-quality scientific summaries
- Prepare presentations for internal and external audiences
- Prepare recommendations for internal and external audiences
- Prepare publication-ready outputs
Berufserfahrung
ca. 1 - 4 Jahre
Ausbildung
Doktor / Ph.D.
Sprachen
Deutsch – fließend
Englisch – fließend
Tools & Technologien
mass spectrometrypeptide mappingintact and subunit level analysischromatographySECIEXRPHICChromeleonEmpowerUniFiGeneData Biologics SuiteExpressionistScreenerChromatics
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