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Research Associate in Cardiovascular and Metabolic Disease Models in vitro (m/w/x)
Designing and executing in-vitro experiments with primary human and animal cell lines. Proficiency in cell culture, molecular biology, and biochemical techniques required. Focus on metabolic pathways and related readouts.
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Anforderungen
- Bachelor's or Master's degree in biology, biochemistry, or related field, or vocational training in biology
- Proficiency in cell culture, molecular biology, and biochemical techniques
- Familiarity with metabolic and/or cardiovascular cellular models
- Effective written and oral English communication
- Ability to interact skillfully with people
- Strong commitment to teamwork
- Strong organizational skills
- Excellent data management skills
- Excellent record-keeping skills
- Experience with animal handling, treatment and functional metabolic experimentation is advantageous
Aufgaben
- Design and execute in-vitro experiments using complex cellular models
- Cultivate primary cell lines from human and animal tissues
- Optimize protocols for primary cell isolation, differentiation, and maintenance
- Execute functional cell-based and enzymatic assays
- Study metabolic pathways and related readouts (e.g., lipolysis, glucose uptake, cAMP signaling)
- Perform advanced cellular and biochemical techniques (e.g., cell painting)
- Evaluate cellular bioenergetics using metabolic flux analysis (e.g., Seahorse)
- Perform standard molecular biology techniques (e.g., qPCR, Western Blot, Immunohistochemistry)
- Analyze experimental data with statistical tools
- Prepare high-quality reports and presentations
- Communicate findings effectively
- Handle animals, administer treatments, and conduct functional metabolic experimentation
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